Publications
Venugopal, B, Mogha, P, Dhawan, J and Majumder, A. (2018) Inter-cellular Force Interaction Overrides Cellular Response to Substrate Stiffness in human Mesenchymal Stem Cells Biomaterials Science (accepted)
Sowpati DT*, Srivastava S*, Dhawan J and Mishra RK (2017) C-State: An interactive web app for simultaneous multi-gene visualization and comparative epigenetic pattern search BMC Bioinformatics 18(Suppl 10):392
Srivastava S, Gala H, Mishra RK and J. Dhawan (2016) Distinguishing states of arrest: Genome-wide descriptions of cellular quiescence using ChIP-seq and RNA-seq analysis Methods in Molecular Biology Daniel Lacorazza (Ed) (in press) (Invited article)
Vyas, N* and J. Dhawan (2016) Exosomes: mobile platforms for targeted and synergistic signaling across cell boundaries. Cell. Mol. Life Sci. DOI 10.1007/s00018-016-2413-9 *corresponding author
J. Sellathurai, J. Nielsen, J. Dhawan, MFB Nielsen, HD Schrøder Low oxygen tension enhances expression of myogenic genes when human myoblasts are activated from G0 arrest PLOS One (2016) 11:e0158860. doi: 10.1371/ journal. pone. 0158860.
Arora R, Rumman, M, Venugopal N, Gala HP and J. Dhawan (2015) Mimicking muscle stem cell quiescence in culture: methods for synchronization in reversible arrest Methods in Molecular Biology, Vol. 1556, Eusebio Perdiguero and Dawn Cornelison (Eds): Muscle Stem Cells, 978-1-4939-6769-8, 329459_1_En, (15) (Invited article)
Dhawan, J. and Laxman, S. (2015) Decoding the stem cell quiescence cycle: lessons from yeast for regenerative biology. (Opinion) J. Cell Sci. 128, 4467-4474 doi:10.1242/jcs.177758
Cheedipudi, S. Gala, HP, Puri DR, J. Dhawan (2015) Identification of PRDM2 regulated genes in quiescent C2C12 myoblasts (2015) Genomics Data 6 (2015) 264–266
Srivastava, S.,* J. Dhawan and R.K. Mishra (2015) Epigenetic mechanisms and boundaries in the regulation of mammalian Hox clusters. Mech Dev. 2015 Nov;138 Pt 2:160-9. doi: 10.1016/j.mod.2015.07.015. *corresponding author
Cheedipudi, S*, Puri DR*, Saleh, A, Gala, HP, Rumman, M, Pillai, MS, Sreenivas, P. Arora, R, Sellathurai, J, Schroeder, HD, Mishra, RK and Dhawan, J. (2015). A fine balance: Epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the Cyclin A gene. Nucleic Acids Res. Jun 3. pii: gkv567. [Epub ahead of print]. *equal contribution
Rumman, M., Dhawan, J. and Kassem, M. (2015) Quiescence in Adult Stem Cells: Biological Significance and Relevance to Tissue Regeneration (review). Stem Cells Jun 15. doi:10.1002/stem.2056
Puri, D., Gala, H., Mishra, R. and Dhawan, J. (2014) High-wire act: The poised genome and cellular memory. (Invited review in Special volume on Epigenetics). FEBSJ Dec 2014
N Vyas*, A Walvekar, D Tate, V Lakshmanan, D Bansal, A Lo Cicero, G Raposo, Da Palakodeti, and J Dhawan (2014) Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties. Sci Rep. 4:7357 *corresponding author
Vishvakarma, R, Raghavan, S, Kuyyamudi, C, Majumder A, Dhawan, J and Pullarkat, PA (2014) Role of actin filaments in correlating nuclear shape and cell spreading. PLOS One 9(9):e107895
Srivastava, S, D. Sowpati, H. Garapati, D. Puri, J. Dhawan, RK Mishra (2014) A ChIP-on-chip tiling array approach detects functional histone-free regions associated with boundaries at vertebrate HOX genes Genomics Data 2 78-81
Subramaniam, S., Prethish, S., Cheedipudi, S, Reddy, VR, Shashidhara, LS, Ravi Kumar Ch., Mylavarapu M, and J. Dhawan. (2013) Distinct transcriptional networks in quiescent myoblasts: a role for Wnt signaling in reversible vs. irreversible arrest PLOS One 8(6):e65097.doi: 10.1371/journal.pone.0065097.
Sellathurai, J., Cheedipudi, S., Dhawan, J., Schrøder, H. (2013) A novel in vitro model for studying quiescence and activation of primary isolated human myoblasts PLOS One 8(5):e64067. doi: 10.1371/journal.pone.0064067.
Srivastava, S., Puri, D., Garapati, H.S., Dhawan, J. and Mishra, R. (2013) Vertebrate GAGA factor associated insulator elements demarcate homeotic genes in the HOX clusters Epigenetics & Chromatin 6(1):8. doi: 10.1186/1756-8935-6-8.
Majumder A, Dhawan J, Levy O, Karp JM (2013). Applications of Microfabrication and Microfluidic Techniques in Mesenchymal Stem Cell Research in Microfluidic Technologies for Human Health, Published by World Scientific USA: pp. 69-95.
Krishna S, Nair A, Cheedipudi S, Poduval D, Dhawan J, Palakodeti D, Ghanekar Y. (2013). Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata Nucleic Acids Res. 7;41:599-616
Puri,D.R., Dhawan, J. and Mishra, R. (2010). The paternal hidden agenda: Epigenetic inheritance through sperm chromatin Epigenetics. 5(5) 386-91.
Srivastava, S., Mishra, R.K. and J. Dhawan. (2010). Regulation of cellular chromatin state: insights from quiescence and differentiation. (invited review) Organogenesis 6:37-47.
Andrews, P., et al. (2009) Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes- International Cell Banking Initiative. Stem Cell Rev. and Rep. 5(4):301-14.
Sambasivan, R., Cheedipudi, S., Pasupuleti, N., Saleh, A., Pavlath, G.K. and Dhawan, J. (2009). The small chromatin protein p8/Nupr1 co-ordinates anti-proliferative and pro-myogenic proteins targeting the Myogenin promoter J. Cell Sci. 122:3481-91.
Sebastian, S., Sreenivas, P., Ramkumar, S., Prashanth, K., Cheedipudi,S., Pavlath G.K. and Dhawan, J. (2009). MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses Cyclin A2, expression, and promotes myogenic differentiation. Proc. Natl. Acad. Sci. USA. 106: 4719-4724.
Sambasivan, R., Pavlath, G.K. and Dhawan, J. (2008) A gene trap strategy identifies quiescence-induced genes in synchronized myoblasts. J. Biosci. 33 :27-44.
Mohit, P., Makhajani, K., Madhavi, M.B., Bharathi, V., Lal, A., Sirdesai, G., Reddy, V.R., Ramesh, P., Kannan, R., Dhawan, J., Shashidhara, LS (2006) Modulation of AP and DV signalling pathways by the homeotic gene Ultrabithorax during haltere development in Drosophila Dev. Biol. 291: 356-367.
Dhawan, J., Gokhale, R.S. and Verma, I.M. (2005) Bioscience in India: times are changing. Cell 123:743-745. (Science Commentary)
Dhawan, J. and Rando, T.A. (2005). Stem Cells in Postnatal Myogenesis: Molecular Mechanisms of Satellite Cell Quiescence, Activation and Replenishment. Trends Cell Biol. 15:666-676.
Dhawan, J. and Helfman, D.M. (2004) Modulation of acto-myosin contractility in skeletal muscle myoblasts uncouples growth arrest from differentiation. J Cell Sci 117: 3735-3748.
Sachidanandan, C. and Dhawan, J. (2003) Skeletal Muscle Progenitor Cells in Development and Regeneration. Proc. Indian Natn. Sci. Acad., B69 (5) 719-740.
Sachidanandan, C., Ramkumar, S. and Dhawan, J. (2002) Tristetraprolin and LPS-inducible CXC chemokine are transiently induced in presumptive satellite cells in response to skeletal muscle injury. J. Cell. Sci. 115 (13) 2701-2712.
Muralikrishna, Bh., Dhawan, J., Rangaraj, N. and Parnaik, V.K. (2001). Distinct changes in intranuclear lamin A/C organization during myoblast differentiation. J. Cell Sci. 114: 4001-4011.
Disatnik, M-H., Dhawan, J., Yu, Y., Beal, M.F., Whirl, MM, Franco, A.A. and Rando, T.A. (1998) Evidence of oxidative injury in mdx mouse muscle : Studies of the pre-necrotic state. J. Neurol Sci. 161: 77-84.
Dhawan, J., Rando, T.A., Elson, S., Lee, F., Stanley, E.R. and Blau, H.M. (1996) Myoblast-mediated delivery of macrophage colony stimulating factor (CSF-1) in the cytokine-deficient osteopetrotic (op/op) mouse. Somat. Cell and Mol. Genet. 22 :363-381
Dhawan, J., Rando, T. A., Elson, S., Bujard, H. and Blau, H.M. (1995) Tetracycline-regulated gene expression after DNA injection into mouse skeletal muscle. Somat. Cell and Mol. Genet. 21: 233-240.
Milasincic, D., Dhawan, J. and Farmer S.R. (1996) Anchorage-dependent control of muscle-specifc gene expression in C2C12 mouse myoblasts. In Vitro Cell. & Dev. Biol. 32 : 90-99.
Dhawan, J. and Blau, H.M. (1994) Systemic delivery of recombinant proteins by genetically engineered myoblasts. In Trends and Future Perspectives in Peptide and Protein Drug Delivery. (V.H. Lee, M. Hashida and Y. Mizushima, eds.) Harwood Publishers, Ltd. Oxford, pp 351-364.
Dhawan, J. and Farmer S.R. (1994) Induction of type I collagen expression in response to adhesion and TGF-B is dependent on microfilament organization. Advances in Expt. Med. and Biol. 358:159-168.
Blau, H.M., Pavlath, G.K. and Dhawan, J. (1993) Myoblast mediated gene therapy. In Tissue Engineering (E. Bell, ed.) Birkhauser, Inc., Boston, pp 37-42.
Blau, H.M., Dhawan, J. and Pavlath, G.K. (1993) Myoblasts in pattern formation and gene therapy. Trends Genet. 9: 269-274.
Dhawan, J., Pan, L.C., Pavlath, G.K., Travis, M.A., Lanctot, A.M., and Blau, H.M. (1991) Systemic delivery of human growth hormone by injection of genetically engineered myoblasts. Science 254:1509-1512.
Dhawan, J., Lichtler, A., Rowe, D. and Farmer, S.R. (1991) Cell adhesion regulates pro alpha 1(I) collagen mRNA stability and transcription in mouse fibroblasts. J.Biol.Chem. 266:8470-8475.
Dhawan, J. and Farmer, S.R. (1990) Regulation of alpha 1(I) collagen expression in response to cell adhesion in Swiss 3T3 fibroblasts. J.Biol.Chem. 265:9015-9021.
Sowpati DT*, Srivastava S*, Dhawan J and Mishra RK (2017) C-State: An interactive web app for simultaneous multi-gene visualization and comparative epigenetic pattern search BMC Bioinformatics 18(Suppl 10):392
Srivastava S, Gala H, Mishra RK and J. Dhawan (2016) Distinguishing states of arrest: Genome-wide descriptions of cellular quiescence using ChIP-seq and RNA-seq analysis Methods in Molecular Biology Daniel Lacorazza (Ed) (in press) (Invited article)
Vyas, N* and J. Dhawan (2016) Exosomes: mobile platforms for targeted and synergistic signaling across cell boundaries. Cell. Mol. Life Sci. DOI 10.1007/s00018-016-2413-9 *corresponding author
J. Sellathurai, J. Nielsen, J. Dhawan, MFB Nielsen, HD Schrøder Low oxygen tension enhances expression of myogenic genes when human myoblasts are activated from G0 arrest PLOS One (2016) 11:e0158860. doi: 10.1371/ journal. pone. 0158860.
Arora R, Rumman, M, Venugopal N, Gala HP and J. Dhawan (2015) Mimicking muscle stem cell quiescence in culture: methods for synchronization in reversible arrest Methods in Molecular Biology, Vol. 1556, Eusebio Perdiguero and Dawn Cornelison (Eds): Muscle Stem Cells, 978-1-4939-6769-8, 329459_1_En, (15) (Invited article)
Dhawan, J. and Laxman, S. (2015) Decoding the stem cell quiescence cycle: lessons from yeast for regenerative biology. (Opinion) J. Cell Sci. 128, 4467-4474 doi:10.1242/jcs.177758
Cheedipudi, S. Gala, HP, Puri DR, J. Dhawan (2015) Identification of PRDM2 regulated genes in quiescent C2C12 myoblasts (2015) Genomics Data 6 (2015) 264–266
Srivastava, S.,* J. Dhawan and R.K. Mishra (2015) Epigenetic mechanisms and boundaries in the regulation of mammalian Hox clusters. Mech Dev. 2015 Nov;138 Pt 2:160-9. doi: 10.1016/j.mod.2015.07.015. *corresponding author
Cheedipudi, S*, Puri DR*, Saleh, A, Gala, HP, Rumman, M, Pillai, MS, Sreenivas, P. Arora, R, Sellathurai, J, Schroeder, HD, Mishra, RK and Dhawan, J. (2015). A fine balance: Epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the Cyclin A gene. Nucleic Acids Res. Jun 3. pii: gkv567. [Epub ahead of print]. *equal contribution
Rumman, M., Dhawan, J. and Kassem, M. (2015) Quiescence in Adult Stem Cells: Biological Significance and Relevance to Tissue Regeneration (review). Stem Cells Jun 15. doi:10.1002/stem.2056
Puri, D., Gala, H., Mishra, R. and Dhawan, J. (2014) High-wire act: The poised genome and cellular memory. (Invited review in Special volume on Epigenetics). FEBSJ Dec 2014
N Vyas*, A Walvekar, D Tate, V Lakshmanan, D Bansal, A Lo Cicero, G Raposo, Da Palakodeti, and J Dhawan (2014) Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties. Sci Rep. 4:7357 *corresponding author
Vishvakarma, R, Raghavan, S, Kuyyamudi, C, Majumder A, Dhawan, J and Pullarkat, PA (2014) Role of actin filaments in correlating nuclear shape and cell spreading. PLOS One 9(9):e107895
Srivastava, S, D. Sowpati, H. Garapati, D. Puri, J. Dhawan, RK Mishra (2014) A ChIP-on-chip tiling array approach detects functional histone-free regions associated with boundaries at vertebrate HOX genes Genomics Data 2 78-81
Subramaniam, S., Prethish, S., Cheedipudi, S, Reddy, VR, Shashidhara, LS, Ravi Kumar Ch., Mylavarapu M, and J. Dhawan. (2013) Distinct transcriptional networks in quiescent myoblasts: a role for Wnt signaling in reversible vs. irreversible arrest PLOS One 8(6):e65097.doi: 10.1371/journal.pone.0065097.
Sellathurai, J., Cheedipudi, S., Dhawan, J., Schrøder, H. (2013) A novel in vitro model for studying quiescence and activation of primary isolated human myoblasts PLOS One 8(5):e64067. doi: 10.1371/journal.pone.0064067.
Srivastava, S., Puri, D., Garapati, H.S., Dhawan, J. and Mishra, R. (2013) Vertebrate GAGA factor associated insulator elements demarcate homeotic genes in the HOX clusters Epigenetics & Chromatin 6(1):8. doi: 10.1186/1756-8935-6-8.
Majumder A, Dhawan J, Levy O, Karp JM (2013). Applications of Microfabrication and Microfluidic Techniques in Mesenchymal Stem Cell Research in Microfluidic Technologies for Human Health, Published by World Scientific USA: pp. 69-95.
Krishna S, Nair A, Cheedipudi S, Poduval D, Dhawan J, Palakodeti D, Ghanekar Y. (2013). Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata Nucleic Acids Res. 7;41:599-616
Puri,D.R., Dhawan, J. and Mishra, R. (2010). The paternal hidden agenda: Epigenetic inheritance through sperm chromatin Epigenetics. 5(5) 386-91.
Srivastava, S., Mishra, R.K. and J. Dhawan. (2010). Regulation of cellular chromatin state: insights from quiescence and differentiation. (invited review) Organogenesis 6:37-47.
Andrews, P., et al. (2009) Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes- International Cell Banking Initiative. Stem Cell Rev. and Rep. 5(4):301-14.
Sambasivan, R., Cheedipudi, S., Pasupuleti, N., Saleh, A., Pavlath, G.K. and Dhawan, J. (2009). The small chromatin protein p8/Nupr1 co-ordinates anti-proliferative and pro-myogenic proteins targeting the Myogenin promoter J. Cell Sci. 122:3481-91.
Sebastian, S., Sreenivas, P., Ramkumar, S., Prashanth, K., Cheedipudi,S., Pavlath G.K. and Dhawan, J. (2009). MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses Cyclin A2, expression, and promotes myogenic differentiation. Proc. Natl. Acad. Sci. USA. 106: 4719-4724.
Sambasivan, R., Pavlath, G.K. and Dhawan, J. (2008) A gene trap strategy identifies quiescence-induced genes in synchronized myoblasts. J. Biosci. 33 :27-44.
Mohit, P., Makhajani, K., Madhavi, M.B., Bharathi, V., Lal, A., Sirdesai, G., Reddy, V.R., Ramesh, P., Kannan, R., Dhawan, J., Shashidhara, LS (2006) Modulation of AP and DV signalling pathways by the homeotic gene Ultrabithorax during haltere development in Drosophila Dev. Biol. 291: 356-367.
Dhawan, J., Gokhale, R.S. and Verma, I.M. (2005) Bioscience in India: times are changing. Cell 123:743-745. (Science Commentary)
Dhawan, J. and Rando, T.A. (2005). Stem Cells in Postnatal Myogenesis: Molecular Mechanisms of Satellite Cell Quiescence, Activation and Replenishment. Trends Cell Biol. 15:666-676.
Dhawan, J. and Helfman, D.M. (2004) Modulation of acto-myosin contractility in skeletal muscle myoblasts uncouples growth arrest from differentiation. J Cell Sci 117: 3735-3748.
Sachidanandan, C. and Dhawan, J. (2003) Skeletal Muscle Progenitor Cells in Development and Regeneration. Proc. Indian Natn. Sci. Acad., B69 (5) 719-740.
Sachidanandan, C., Ramkumar, S. and Dhawan, J. (2002) Tristetraprolin and LPS-inducible CXC chemokine are transiently induced in presumptive satellite cells in response to skeletal muscle injury. J. Cell. Sci. 115 (13) 2701-2712.
Muralikrishna, Bh., Dhawan, J., Rangaraj, N. and Parnaik, V.K. (2001). Distinct changes in intranuclear lamin A/C organization during myoblast differentiation. J. Cell Sci. 114: 4001-4011.
Disatnik, M-H., Dhawan, J., Yu, Y., Beal, M.F., Whirl, MM, Franco, A.A. and Rando, T.A. (1998) Evidence of oxidative injury in mdx mouse muscle : Studies of the pre-necrotic state. J. Neurol Sci. 161: 77-84.
Dhawan, J., Rando, T.A., Elson, S., Lee, F., Stanley, E.R. and Blau, H.M. (1996) Myoblast-mediated delivery of macrophage colony stimulating factor (CSF-1) in the cytokine-deficient osteopetrotic (op/op) mouse. Somat. Cell and Mol. Genet. 22 :363-381
Dhawan, J., Rando, T. A., Elson, S., Bujard, H. and Blau, H.M. (1995) Tetracycline-regulated gene expression after DNA injection into mouse skeletal muscle. Somat. Cell and Mol. Genet. 21: 233-240.
Milasincic, D., Dhawan, J. and Farmer S.R. (1996) Anchorage-dependent control of muscle-specifc gene expression in C2C12 mouse myoblasts. In Vitro Cell. & Dev. Biol. 32 : 90-99.
Dhawan, J. and Blau, H.M. (1994) Systemic delivery of recombinant proteins by genetically engineered myoblasts. In Trends and Future Perspectives in Peptide and Protein Drug Delivery. (V.H. Lee, M. Hashida and Y. Mizushima, eds.) Harwood Publishers, Ltd. Oxford, pp 351-364.
Dhawan, J. and Farmer S.R. (1994) Induction of type I collagen expression in response to adhesion and TGF-B is dependent on microfilament organization. Advances in Expt. Med. and Biol. 358:159-168.
Blau, H.M., Pavlath, G.K. and Dhawan, J. (1993) Myoblast mediated gene therapy. In Tissue Engineering (E. Bell, ed.) Birkhauser, Inc., Boston, pp 37-42.
Blau, H.M., Dhawan, J. and Pavlath, G.K. (1993) Myoblasts in pattern formation and gene therapy. Trends Genet. 9: 269-274.
Dhawan, J., Pan, L.C., Pavlath, G.K., Travis, M.A., Lanctot, A.M., and Blau, H.M. (1991) Systemic delivery of human growth hormone by injection of genetically engineered myoblasts. Science 254:1509-1512.
Dhawan, J., Lichtler, A., Rowe, D. and Farmer, S.R. (1991) Cell adhesion regulates pro alpha 1(I) collagen mRNA stability and transcription in mouse fibroblasts. J.Biol.Chem. 266:8470-8475.
Dhawan, J. and Farmer, S.R. (1990) Regulation of alpha 1(I) collagen expression in response to cell adhesion in Swiss 3T3 fibroblasts. J.Biol.Chem. 265:9015-9021.